Important Information for Kilimanjaro
The Side Effects of Taking Diamox for Altitude Sickness
The Side Effects of Taking Diamox for Altitude Sickness

The Side Effects of Taking Diamox for Altitude Sickness

If you plan to climb Mount Kilimanjaro or trek to any high-altitude destination, you may have heard about Diamox (acetazolamide) as a medication to help prevent altitude sickness. While Diamox can be highly effective at combating the symptoms of acute mountain sickness (AMS), it’s essential to understand its potential side effects of taking Diamox before deciding to use it.

In this article, we’ll cover what Diamox is, how it works, and the common and rare side effects you should be aware of.

What Is Diamox and How Does It Work?

acetazolamide also known as diamox for KilimanjaroDiamox is the brand name for acetazolamide, a medication that helps your body adjust to high altitudes by speeding up acclimatization. It works by stimulating breathing, which helps increase the amount of oxygen in your bloodstream. This effect reduces symptoms of altitude sickness, such as headaches, dizziness, nausea, and fatigue.

For climbers attempting peaks like Kilimanjaro, Diamox can be a helpful tool to reduce the risk of AMS when taken as a preventative measure.

Hiking toward barafu hut 14,800 feet

Common Side Effects of Diamox

While Diamox can be a game-changer for high-altitude climbs, it comes with side effects. Here are some of the most common ones:

Frequent Urination

Diamox is a diuretic, which means it increases urine production. This can lead to frequent bathroom breaks, especially at night, which can be inconvenient on a climb.

Tingling Sensation (Paresthesia)

Many users report a tingling or “pins and needles” sensation in their fingers, toes, and face. While harmless, this side effect can feel strange and uncomfortable.

Increased Thirst and Dry Mouth

Because Diamox causes your body to expel more fluids, you may experience dehydration, dry mouth, or excessive thirst. Staying well-hydrated is crucial when taking this medication.

Nausea or Upset Stomach

Some climbers report mild gastrointestinal issues, including nausea, diarrhea, or an upset stomach. Taking the medication with food can help reduce this effect.

Taste Alterations

Foods and beverages, particularly carbonated drinks, may taste strange or metallic while using Diamox. This change in taste can be annoying but usually goes away once you stop taking the medication.

You are more susceptible to sunburn

Kilimanjaro summit

Make sure to wear sunscreen and long-sleeved shirts, sunhats, and buffs.

You may lose your nearsightedness for a few days.

Diamox is used to trerat Glacoma. If you choose to use it, don’t just stop taking it once you reach the summit, ween yourself off it by reducing the dosage for a few days.

Rare but Serious Side Effects

While rare, some individuals may experience more serious side effects when taking Diamox. If you experience any of the following, you should stop taking the medication and seek medical advice immediately:

Severe Allergic Reactions

Symptoms such as rash, hives, difficulty breathing, or swelling of the lips, tongue, or throat could indicate a severe allergic reaction.

Severe Fatigue or Weakness

If you feel unusually weak or excessively tired, it may be a sign of an adverse reaction.

Blood Disorders

In extremely rare cases, Diamox can affect blood cell production, leading to anemia or other blood-related issues.

Kidney Stones

kidney stones from Diamox

Prolonged use of Diamox can increase the risk of kidney stones due to changes in the acid-base balance of your body. Staying hydrated can help minimize this risk.

Hearing Issues

Hearing loss or ringing in the ears (tinnitus) is a rare side effect of Diamox.

Who Should Avoid Diamox?

Certain individuals should avoid using Diamox or consult their physician before taking it:

  • People allergic to sulfa drugs (Diamox is a sulfonamide derivative).
  • Those with kidney or liver disease.
  • Individuals with adrenal gland problems or electrolyte imbalances.
  • Pregnant or breastfeeding women (consult your doctor before use).
  • Tips for Taking Diamox Safely

If you decide to use Diamox for altitude sickness prevention, here are some tips to minimize side effects:

Start with a Test Dose

Before your trip, take a small dose at home to see how your body reacts to the medication.

Stay Hydrated

Stay hydrated on Kilimanjaro
Photo: Cottonbro Studio

Drink plenty of water to counteract the diuretic effects and avoid dehydration.

Take It with Food

Taking Diamox with food can help reduce nausea and stomach discomfort.

Follow Dosage Instructions

Typically, climbers take 125-250 mg of Diamox twice daily, starting 1-2 days before ascending and continuing for 2-3 days at altitude.

Communicate with Your Doctor

Consult a physician to confirm that Diamox is appropriate for you, especially if you have underlying health conditions.

Final Thoughts

Diamox is a valuable tool for high-altitude travelers to reduce the risk of altitude sickness, but it’s not without side effects. While most side effects of taking Diamox are mild and manageable, it’s important to be aware of them and to use the medication responsibly.

If you’re planning a climb to Kilimanjaro or another high-altitude trek, consult your doctor to determine whether Diamox is right for you. Remember to prioritize acclimatization techniques, like ascending gradually and staying hydrated, to further reduce your risk of AMS.

Original article posted on Kilimanjarosunrise.com